Gastroenteropancreatic Neuroendocrine Tumor Disease: Molecular and Cell Biological Aspects

Gastroenteropancreatic Neuroendocrine Tumor Disease: Molecular and Cell Biological Aspects

Author: Bertram Wiedenmann

Format: Paperback

Pages: 302

ISBN: 9781573314923

Language: English

Publisher: New York Academy of Sciences

Release Date: May 31, 2004

Description du Livre

At the beginning of the last century, the development of the Neuroendocrine Concept sparked intensive and worldwide research efforts leading to fascinating insights into the complex and diverse system of neuroendocrine cells and its importance in human physiology and disease. Recent developments in new and expanding research areas, including developmental biology, regulation of angiogenesis, cellular signaling and transcription, and impressive results obtained by application of genomics and proteomics warranted a reevaluation of the neuroendocrine concept. impact of the current understanding of neuroendocrine biology and pathobiology in these research areas. In particular, new discoveries are presented in neuroendocrine developmental biology with special emphasis on transcription factors controlling neuroendocrine differentiation of endodermal stem cells. controlling formation and proliferation of blood and lymphatic vessels and molecular determinants of hematogenous and lymphatic tumor dissemination. Given their central importance for the establishment and maintenance of the neuroendocrine phenotype, signal transduction cascades and their cellular targets related to the regulation of adhesion processes, receptor-mediated endocytosis, and cell cycle events as well as secretory activation and membrane trafficking are discussed in the context of neuroendocrine physiology and neuroendocrine tumor disease. Since many of the recent discoveries made in basic research can be directly linked to clinical applications, this volume summarizes and discusses innovative treatment and/or diagnostic approaches for neuroendocrine tumor disease.

Commentaires
Andrée Bédard
Je vous recommanderai à mes collègues. Leur miracle de Noël est les livres les plus précieux que nous ayons jamais achetés. Je serais perdu sans ça. Je suis complète ment époustouflé.
Émilie Aucoin
Mes amis sont tellement fous qu’ils ne savent pas comment j’ai tous les ebook de haute qualité qu’ils n’ont pas!
Alphonse Ratté
Je tiens à vous remercier personnellement pour vos livres exceptionnels. C’est vraiment merveilleux.
Blanchefle Morneau
Enfin, je reçois cet ebook, merci pour tous ces miracles de Noël que je peux obtenir maintenant!
Gradasso Martel
Leur Miracle de Noel était le meilleur livre que j’ai jamais acheter. Leur Miracle de Noel a fait exactement ce que tu as dit qu’il faisait.